Numerical study on significance of wind action on 2-D freak waves with different parameters

This paper presents a numerical study on how the significance of wind action differs when varying the wave parameters. The quasi arbitrary Lagrangian-Eulerian finite element method (QALE-FEM) is used for this purpose. An improved model for wind-excited pressure and wind-driven current, which is recently developed by the authors of this paper [27], is coupled with the QALE-FEM. Many cases involving freak waves with different focusing time/point and frequency ranges under the action of winds are investigated. The results show that the significance of wind actions on freak waves strongly depends on the focusing time, the focusing point and the frequency range. The knowledge does not only help the proper set up of experiments studying wind effects on freak waves but also contributes to the development of a method for predicting freak waves

A hybrid approach coupling mlpg-r with QALE-FEM for modelling fully nonlinear water waves

The paper reports a progress on the development of a hybrid approach coupling the Meshless Local Petrov-Galerkin Method based on Rankine Solution (MLPG-R) and the Quasi Arbitrary Langangian-Eulerian Finite Element Method (QALE-FEM) for modelling nonlinear water waves. The former is to solve the one-phase incompressible Naiver-Stokes model using a fractional step method (projection method), whereas the latter is to solve the Fully Nonlinear Potential Theory (FNPT) using a time-marching procedure. They are fully coupled using a zonal approach. The hybrid approach takes the advantage of the QALE-FEM on modelling fully nonlinear water waves with relatively higher computational efficiency and that of the MLPG-R on its capacity on dealing with viscous effects and breaking waves. The model is validated by comparing the numerical prediction with the experimental data for a unidirectional focusing wave. A good agreement has been achieved

Microlensing of Sub-parsec Massive Binary Black Holes in Lensed QSOs: Light Curves and Size-Wavelength Relation

Sub-parsec binary massive black holes (BBHs) are long anticipated to exist in many QSOs but remain observationally elusive. In this paper, we propose a novel method to probe sub-parsec BBHs through microlensing of lensed QSOs. If a QSO hosts a sub-parsec BBH in its center, it is expected that the BBH is surrounded by a circum-binary disk, each component of the BBH is surrounded by a small accretion disk, and a gap is opened by the secondary component in between the circum-binary disk and the two small disks. Assuming such a BBH structure, we generate mock microlensing light curves for some QSO systems that host BBHs with typical physical parameters. We show that microlensing light curves of a BBH QSO system at the infrared-optical-UV bands can be significantly different from those of corresponding QSO system with a single massive black hole (MBH), mainly because of the existence of the gap and the rotation of the BBH (and its associated small disks) around the center of mass. We estimate the half-light radii of the emission region at different wavelengths from mock light curves and find that the obtained half-light radius vs. wavelength relations of BBH QSO systems can be much flatter than those of single MBH QSO systems at a wavelength range determined by the BBH parameters, such as the total mass, mass ratio, separation, accretion rates, etc. The difference is primarily due to the existence of the gap. Such unique features on the light curves and half-light radius-wavelength relations of BBH QSO systems can be used to select and probe sub-parsec BBHs in a large number of lensed QSOs to be discovered by current and future surveys, including the Panoramic Survey Telescope and Rapid Response System (Pan-STARRS), the Large Synoptic Survey telescope (LSST) and Euclid.Comment: 18 pages, 17 figures, accepted for publication in the Astrophysical Journa

Phenotypic and Genotypic Characteristics of Methicillin-Resistant Staphylococcus aureus (MRSA) Related to Persistent Endovascular Infection.

Persistent methicillin-resistant Staphylococcus aureus (MRSA) bacteremia (PB) represents an important subset of S. aureus infection and correlates with poor clinical outcomes. MRSA isolates from patients with PB differ significantly from those of resolving bacteremia (RB) with regard to several in vitro phenotypic and genotypic profiles. For instance, PB strains exhibit less susceptibility to cationic host defense peptides and vancomycin (VAN) killing under in vivo-like conditions, greater damage to endothelial cells, thicker biofilm formation, altered growth rates, early activation of many global virulence regulons (e.g., sigB, sarA, sae and agr) and higher expression of purine biosynthesis genes (e.g., purF) than RB strains. Importantly, PB strains are significantly more resistant to VAN treatment in experimental infective endocarditis as compared to RB strains, despite similar VAN minimum inhibitory concentrations (MICs) in vitro. Here, we review relevant phenotypic and genotypic characteristics related to the PB outcome. These and future insights may improve our understanding of the specific mechanism(s) contributing to the PB outcome, and aid in the development of novel therapeutic and preventative measures against this life-threatening infection

A novel approach to modelling and simulating the contact behaviour between a human hand model and a deformable object

A deeper understanding of biomechanical behaviour of human hands becomes fundamental for any human hand-operated Q2 activities. The integration of biomechanical knowledge of human hands into product design process starts to play an increasingly important role in developing an ergonomic product-to-user interface for products and systems requiring high level of comfortable and responsive interactions. Generation of such precise and dynamic models can provide scientific evaluation tools to support product and system development through simulation. This type of support is urgently required in many applications such as hand skill training for surgical operations, ergonomic study of a product or system developed and so forth. The aim of this work is to study the contact behaviour between the operators’ hand and a hand-held tool or other similar contacts, by developing a novel and precise nonlinear 3D finite element model of the hand and by investigating the contact behaviour through simulation. The contact behaviour is externalised by solving the problem using the bi-potential method. The human body’s biomechanical characteristics, such as hand deformity and structural behaviour, have been fully modelled by implementing anisotropic hyperelastic laws. A case study is given to illustrate the effectiveness of the approac

A study on inclusion formation mechanism in alpha-LiIO sub 3 crystals

The spatial distribution of inclusions in alpha-LiIO3 crystals by means of an argon laser beam scanning technique is studied. The effects of crystal dimensions and solution fluid flow on the inclusion formation in the alpha-LiIO3 crystals were observed. It was further shown that the fluid flow plays an important role in the formation of inclusions. The results obtained were further applied and verified by growing a perfect alpha-LiIO3 single crystal. An experimental foundation for further theoretical studies on the causes of inclusions may be provided

Hawking Radiation of an Arbitrarily Accelerating Kinnersley Black Hole: Spin-Acceleration Coupling Effect

The Hawking radiation of Weyl neutrinos in an arbitrarily accelerating Kinnersley black hole is investigated by using a method of the generalized tortoise coordinate transformation. Both the location and temperature of the event horizon depend on the time and on the angles. They coincide with previous results, but the thermal radiation spectrum of massless spinor particles displays a kind of spin-acceleration coupling effect.Comment: 8 pages, no figure, revtex 4.0, revisted version with typesetting errors and misprint correcte